Source Naturals Natural Progesterone Cream features natural progesterone USP from soy. Massage 1/4 to 1/2 teaspoon of cream twice daily into smooth skin areas such as the wrists, inner arms or thighs, throat, abdomenen, or chest. Premenopausal women use for 14 days prior to the first day of menstruation, discontinue and repeat. Menopausal and post menopausal women use for 21 ays, discontinue for 7 days and repeat. These are general recommendations only and may need to be modified for individual needs. Please consult your health care professional for specific situations.